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Animals In Print
The On-Line Newsletter

From 12 December 2006 Issue

Warning, Adverse Drug Reaction, Previcox Is It safe?

The following is an email sent to Jean Townsend concerning a drug, Previcox. I encourage all my subscribers to read over this information so they may safely medicate their animals without adverse reactions.

Email
"I have a German Shepherd who has hip displasia. She was on Rimadyl, then Deramaxx. Then my vet told me to try 10 day free sample of that horrible drug previcox. I gave it to her for 6 days and I thought she was dying. I was wondering if you knew their web site because I tried previcox.com and no luck. If you have some information on how I can tell their company their drug is so so bad, please help me"

REPLY
"My first advice was to see that your dog is seen as soon as possible by a veterinarian who is knowledgeable about, and admits there are, adverse side effects to these drugs!

Previcox Client Information Sheet: http://www.fda.gov/cvm/Documents/N141230cis.pdf should have been given when drug was prescribed. Contact info is on the site.

Deramaxx Client Info Sheet: http://www.fda.gov/cvm/Documents/N141203cis.pdf (chewable)

Info on Client Info Sheets: http://www.medicalnewstoday.com/youropinions.php?opinionid=10764

Rimadyl Client Info sheet - http://www.fda.gov/cvm/Documents/N141053cis.pdf

If the vet prescribed these drugs, did not do blood work prior to prescribing and did not give the Client Information sheet, it is my opinion this is bordering on malpractice and the vet should be reported to the State's Vet Med Board.

I am taking the liberty of sharing a copy of this with some colleagues of mine who I work with constantly.

They are Demitry Herman, Denise Dost, Ed Murray, Joanna Thurman and Laurryn Simpson.

If these drugs were given without allowing a "washout" time then the vet should go back to school. Here is what Pfizer (Rimadyl manufacturer) says about Rimadyl:

QUOTE: (See: http://www.rimadyl.com/display.asp?country=US&lang=EN&drug=RC&species=CN&sec=610

"Can Rimadyl be given with other medicine?
Rimadyl should not be given with other NSAIDS (for example, aspirin, etodolac) or steroids (for example, cortisone, prednisone, dexamethasone, triamicolone).

Tell your veterinarian about all medicines you have given your dog in the past, and any medications that you are planning to give with Rimadyl. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog's medicines can be given together.
END QUOTE

See also: http://www.rimadyl.com/product_overview.asp?country=US&lang=EN&drug=RC&species=CN&sec=630 

The following is taken from the Dec. 2000 Rimadyl Technical Bulletin and it speaks of "washout" periods before switching from one NSAID to another - or from an NSAID to a STEROID!

QUOTE:
Table 1: Withdrawal (washout) times
Once one NSAID is discontinued, a minimum of 48 to 72 hours should be allowed before initiation of another NSAID. When switching from aspirin to another NSAID, a washout period of 10 to 14 days is
advised to minimize the carryover of aspirin-induced platelet dysfunction. Prednisone to an NSAID—allow at least 1 week. Long-acting corticosteroid to an NSAID—allow at least 3 to 4 weeks.
END QUOTE

Please stay in touch and let me know how the dog gets along, and if you contact the manufacturer - An adverse drug effect report should, in my opinion - and I am neither a vet nor a vet tech - me made to the manufacturers of these drugs and to the FDA Center for Veterinary Medicine.

Some web sites with lots of information and help:
http://dogsadversereactions.com/
http://dogsadversereactions.com/fdareporting.html

Jean Townsend - Johns Island, SC
(Always for George - Always for the Rimadyl Dogs)
http://dogsadversereactions.com/nsaid/memorials.html#george
http://dogsadversereactions.com/nsaid/survivors6.html

Go on to Global warming already killing species, analysis says
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Please send comments and submittals to the Editor: Linda Beane Ljbeane1@aol.com

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