University of Michigan, Ann Arbor, MI

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Stop Animal Exploitation NOW!
S. A. E. N.
"Exposing the truth to wipe out animal experimentation"

Government Grants Promoting Cruelty to Animals

University of Michigan, Ann Arbor, MI

GAIL D. WINGER - Primate Testing - 1976

Grant Number: 1R01AA002644-01
Project Title: MODIFICATION OF ALCOHOL SELF-INFUSION
PI Information: RESEARCH PROFESSOR GAIL D. WINGER,  gwinger@umich.edu 

Abstract: The primary thrust of this grant proposal is to pursue findings obtained in earlier work and in preliminary investigations which indicate that intravenous alcohol self-administration can be modified by drug pretreatment, might be modified by physical dependence development, but might not be altered by tolerance development. In three separate studies, rhesus monkeys with chronically implanted venous catheters will receive intravenous infusions of alcohol, contingent on lever responses and according to schedules of reinforcement. Variables of access time and non-contingent infusions of alcohol and other drugs will be appropriately manipulated and effects observed on rates and patterns of both alcohol and food-reinforced responding in order to determine the effect of intoxication, tolerance, and dependence on the reinforcing property of alcohol.

Thesaurus Terms:
ALCOHOL RESEARCH REVIEW COMMITTEE, ALCOHOLISM - DRINKING, ALCOHOL CONSUMPTION, MODELS, BIOLOGICAL DOSAGE AND ROUTE, INFUSIONS VENOUS

Institution: UNIVERSITY OF MICHIGAN AT ANN ARBOR
3003 SOUTH STATE STREET, Room 1040
ANN ARBOR, MI 481091274
Fiscal Year: 1976
Department:
Project Start: 20-SEP-1976
Project End: 31-AUG-1979
ICD: NATIONAL INSTITUTE ON DRUG ABUSE
IRG: SRC

Please email:  GAIL D. WINGER, gwinger@umich.edu to protest the inhumane use of animals in this experiment. We would also love to know about your efforts with this cause: saen@saenonline.org

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Rats, mice, birds, amphibians and other animals have been excluded from coverage by the Animal Welfare Act. Therefore research facility reports do not include these animals. As a result of this situation, a blank report, or one with few animals listed, does not mean that a facility has not performed experiments on non-reportable animals. A blank form does mean that the facility in question has not used covered animals (primates, dogs, cats, rabbits, guinea pigs, hamsters, pigs, sheep, goats, etc.). Rats and mice alone are believed to comprise over 90% of the animals used in experimentation. Therefore the majority of animals used at research facilities are not even counted.

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