Home Page
About SAEN
Articles and Reports
Contact Us
Events and Campaigns
Fact Sheets
Financial Information
How You Can Help
Make a Donation, Please!
Media Coverage
Newsletters
Petitions
Picture Archive
Press Releases
Resources and Links
Grass Roots Org. List

Stop Animal Exploitation NOW!
S. A. E. N.
"Exposing the truth to wipe out animal experimentation"

Resources and Links

Facility Reports and Information

Air Force Research Laboratory, Wright-Patterson AFB, OH

DOD Funding of Animal Cruelty 2005: The Acute Effects of Tungsten Alloys on the Airways of Sprague-Dawley Rats (Rattus norvegicu)

Title: The Acute Effects of Tungsten Alloys on the Airways of Sprague-Dawley Rats (Rattus norvegicu)

Research Category:

FY: 2005 Funding (in dollars): 91,000

Responsible Organization: AIR FORCE RESEARCH LAB/WRIGHT PATTERSON
Primary Contact: See Responsible Organization Information
City: Wright-Patterson AFB
State: OH
Zip: 45433-7902

Keywords: LABORATORY ANIMALS TUNGSTEN ALLOYS TUNGSTEN, NICKEL AND COBALT CO-EXPOSURE, INHALATION AEROSOL INTRATRACHEAL INSTILLATION LUNG INFLAMMATION LUNG INJURY TUNGSTEN

Objective: Determine if the persistent airway inflammation observed following a single exposure to tungsten alloys is associated with genotoxic changes and tumor development.

Approach: Adult sprague Dawley rats were intra-tracheally exposed to four different analytes; Tungsten-Nickel-Cobalt (WA1), Tungsten-Nickel-Iron (WA2), Silica (positive response), Titanium dioxide (particle control). These were then grouped into various doses (low, medium, and high) with various times for exposure (24 hour, 3 days, 7 days, 3 months, and 6 months). Macrophage counts were done with lung lavages as well as various cytokine response tests, histopathology, and metal analyses of various tissues.

Return to Air Force Research Laboratory, Wright-Patterson AFB, OH
Return to Ohio
Return to Facility Reports and Information
Return to Resources and Links

Rats, mice, birds, amphibians and other animals have been excluded from coverage by the Animal Welfare Act. Therefore research facility reports do not include these animals. As a result of this situation, a blank report, or one with few animals listed, does not mean that a facility has not performed experiments on non-reportable animals. A blank form does mean that the facility in question has not used covered animals (primates, dogs, cats, rabbits, guinea pigs, hamsters, pigs, sheep, goats, etc.). Rats and mice alone are believed to comprise over 90% of the animals used in experimentation. Therefore the majority of animals used at research facilities are not even counted.

We welcome your comments and questions


This site is hosted and maintained by:
The Mary T. and Frank L. Hoffman Family Foundation
Thank you for visiting all-creatures.org.
Since date.gif (991 bytes)