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Brooks Air Force Base, TX

Protocol - 2003-18 - Ocular Effects of Microwave Radiation

 

Title:

Ocular Effects of Microwave Radiation

Research Category:

M5: Human Systems Technology

FY: 2003 Funding (in dollars):

256,000

Responsible Organization:	AIR FORCE RESEARCH LAB/BROOKS
Primary Contact:	Public Affairs Office
City:	Brooks City-Base
State:	TX
Zip:	78235-5116

Performing Organization:	See Responsible Organization Information
City:
State:
Zip:

Keywords:

LABORATORY ANIMALS PULSED MICROWAVES RETINA EYE MICROWAVES EYE RESONANCE

Objective:

The primary aim of this project for this reporting period was to test previous research findings that microwave exposure, at safety standard levels, would permanently damage the corneal endothelium of the eye. Two studies were conducted to test this hypothesis.

Approach:

The first study was designed to evaluate corneal endothelial damage in anesthetized rhesus monkeys (Macaca mulatta) after pulsed microwave exposures at 2.8 GHz and 94 GHz. Both eyes of four rhesus monkeys were exposed, while anesthetized, to pulsed microwaves at low average power density but with relatively high peak power density. Baseline anterior segment assessment included specular microscopy and pachymetry using a noncontact specular microscope. Images of the central and four peripheral areas of the cornea were examined and photographed. These studies were repeated 7 days, 30days, 90 days, and 180 days after the exposure sequence. The second study was conducted the same as the first to determine if the glaucoma treatment drugs latanoprost, a prostaglandin receptor agonist, and timolol maleate, administered 30 min prior to microwave exposures to the eyes, would produce increased corneal endothelial damage.

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Rats, mice, birds, amphibians and other animals have been excluded from coverage by the Animal Welfare Act. Therefore research facility reports do not include these animals. As a result of this situation, a blank report, or one with few animals listed, does not mean that a facility has not performed experiments on non-reportable animals. A blank form does mean that the facility in question has not used covered animals (primates, dogs, cats, rabbits, guinea pigs, hamsters, pigs, sheep, goats, etc.). Rats and mice alone are believed to comprise over 90% of the animals used in experimentation. Therefore the majority of animals used at research facilities are not even counted.