Biotechnology Companies with Complete or Important Use of Non-Animal Methods
for Drug Development:
Alternatives to Animal Testing
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Alternatives to Animal Testing
Biotechnology Companies with Complete or Important Use of Non-Animal Methods for Drug Development
These are selected companies perhaps of particular interest for their potential to replace and significantly reduce animal drug testing. Many other companies can be found by searching individual company types on Google or other search engine. This is also a work in progress.
Human cells and tissues (including microarrays)
- Affymetrix (microarray industry leader): www.affymetrix.com
- Agilent Technologies (microarrays for genetic expression profiling): www.agilent.com
- APSciences (human cells system for testing toxicity and efficacy) www.apsciences.com
- Asterand, plc (post merger of Asterand, Inc. and Pharmagene, plc): www.asterand.com
- Biopta (CRO focused on “proof of concept in man”): www.biopta.com
- Hurel Corporation (animal and human tissue microfluidics test kits): www.hurelcorp.com
- InVitro International (ocular and dermal irritancy and corrosivity testing): www.invitrointl.com
- Invitrogen (animal-free cell culture media): www.invitrogen.com
- MatTek Corporation (human tissue irritancy and corrosivity models): www.mattek.com
- Stem Cell Innovations (human cell and tissue liver tox assays): www.stemcellinnovations.com
- Solidus Biosciences (“MetaChip and “DataChip” for rapid toxicity testing of human tissue)
- Tissue Therapies (human skin models for cosmetics and wound care): www.tissuetherapies.com
Bioinformatics and In Silico Methods
- BioSim (EC-established multidisciplinary network to develop in silico simulation models for cellular, physiological and pharmacological processes, to improve drug development and to decrease animal drug testing): http://biosim.fysik.dtu.dk:8080/biosim/index.jsp
- Entelos (in silico disease models and virtual patients): www.entelos.com
- Ingenuity Systems (in silico methods for drug pathways analysis): www.ingenuity.com
- Optimata (disease modeling and virtual patients for cancer and CNS): www.optimata.com
- Simcyp (human drug response modeling software and databases): www.simcyp.com
- Simugen, Ltd. (computational biology and gene expression profiling): www.simugen.co.uk
- Stem Cell Innovations (compound databases and software): www.stemcellinnovations.com
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