These vegan health articles are presented to assist you in taking a pro-active part in your own health.
In a recent editorial in the British Medical Journal, several experts from the University of Bristol in England write about the substantial and still growing body of evidence implicating insulin-like growth factor-I (IGF-1) in cancer.
They note that the role of IGF-1 in promoting cancer has been investigated for many years, but recently the quality and quantity of evidence has increased
They note that several prospective studies have used stored blood collected up to 14 years before the onset of cancer have shown associations between IGF-1 and prostate cancer, premenopausal breast cancer, and colon cancer.
According to the editorial, "The risk of cancer is higher among people with raised concentrations of insulin-like growth factor-I".
In addition, "it is lower among those with high concentrations of insulin-like growth factor binding protein-3 (the main binding protein)."
Research suggests that the observed relation between cancer and IGF-1 is not due to the release of the growth factor by the cancer itself.
"The effects are sizeable and stronger than the effects seen in relation to most previously reported risk factors" they state.
In addition to the increasing direct epidemiological evidence, there is a significant amount of circumstantial evidence.
Some of the potential mechanisms of the way in which IGF-1 increases cancer risk are as follows:
"Given the increasing evidence of the risk of cancer, caution should be exercised in the exogenous use of either insulin-like growth factor-I or substances that increase concentrations of it," they state.
British Medical Journal October 7, 2000;321:847-848
DR. MERCOLA'S COMMENT: Many may not realize that when you drink milk you are consuming IGF-1, along with many other growth factors. Milk from cows treated with synthetic growth hormones such as rBGH have especially high levels of IGF-1. This is one of the many reasons why I advise avoiding milk. You can click on the links below for the others.
It is also interesting to note that the growth hormone that is so strongly promoted by many anti-aging clinicians may in fact have adverse effects by raising insulin-like growth factor-I. It is probably best for most to avoid the use of growth hormone and rely on more proven and less risky interventions, like a good diet which reduces insulin levels and also weight training which can increase growth hormone.
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We began this archive as a means of assisting our visitors in answering many of their health and diet questions, and in encouraging them to take a pro-active part in their own health. We believe the articles and information contained herein are true, but are not presenting them as advice. We, personally, have found that a whole food vegan diet has helped our own health, and simply wish to share with others the things we have found. Each of us must make our own decisions, for it's our own body. If you have a health problem, see your own physician.