Alternatives to Animal Testing, Experimentation and Dissection Articles from All-Creatures.org

21st Century Neuroscience

From CAARE Citizens for Alternatives to Animal Research
March 2024

Discussion of high-quality, human-relevant alternatives to animals to study the brain and neurological disorders. With numerous examples of cutting-edge research, they show how human-relevant methods can and must replace this category of animal experiments. Dr. Miller is the author of the 2023 book “The Rise and Fall of Animal Experimentation” and has recently joined CAARE as scientific advisor.

One of the largest categories of animal research involves painful and invasive brain experiments done purportedly to understand the human brain and neurological diseases. While animal experiments routinely fail to model human disease, this area of research has been especially unsuccessful. Most of our neurological and psychiatric diseases are without effective treatments and even fewer have cures.

CAARE’s president, Barbara Stagno, and Richard Miller PhD, Professor Emeritus of Pharmacology at Northwestern University Feinberg School of Medicine have published an article discussing high-quality, human-relevant alternatives to animals to study the brain and neurological disorders. With numerous examples of cutting-edge research, they show how human-relevant methods can and must replace this category of animal experiments. Dr. Miller is the author of the 2023 book The Rise and Fall of Animal Experimentation: Empathy, Science, and the Future of Research and has recently joined CAARE as scientific advisor.

Advances in animal-free research to study neurological disease are growing and improving. Researchers at University of Wisconsin-Madison have refined 3D bioprinted brain tissue that replicates key brain functions and believe it will help us to study diseases like Alzheimer's and Parkinson’s. At University of Essex in the UK, scientists are using AI and brain scans of children who experienced trauma, rather than inflicting stress on baby animals to reveal new information on how trauma impacts developing brain function and provide new directions for treatment.

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Please read the ENTIRE ARTICLE HERE, including:

• Moving past animal experiments to understand human neurological disease
• NIH statement on catalyzing the development of non-animal methods
• Researchers 3D-print functional human brain tissue
• World's largest childhood trauma study uncovers brain rewiring

 

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