
Rats in isolation cages
The Animal Resource Centre (ARC) in Western Australia, a government
subsidized facility that supplies mice and rats to laboratories,
recently announced its upcoming closure due to financial
difficulties. This closure presents a unique opportunity for the
Australian government to invest in non-animal research rather than
strive to perpetuate outdated animal experiments.
Please send a polite letter to ask the National Health and Medical
Research Council (NHMRC) of Australia to redirect funding to
superior, human-relevant alternatives.
ARC is a major supplier of mice and rats to laboratories in
Australia and other parts of the world. While some researchers are
fretting about losing access to animals, others are speaking out
about the urgent need to replace animals with superior,
human-relevant alternatives.
Dr. Bret Lidbury, a scientific advisor to Humane Research Australia,
points out, “Animal models are 90-95% ineffective at predicting
human disease. The overwhelming evidence suggests animal models are
in no way the best way to study human disease.”
“There are credible advances away from animal models,” he notes,
“but getting those alternatives validated and accepted by broader
research culture is proving difficult…There is almost no significant
funding to take alternatives and run large validation studies”.
The ARC is the second substantial facility of its type to close in the past two years. In 2019, the Wellcome Sanger Institute in the UK shut down its animal research facility that bred thousands of genetically modified mice, shifting its focus to human relevant research such as advanced organoids and the Human Cell Atlas Project.

Cellular test
When the Sanger Institute closed, biotech entrepreneur, Dr. Jonathan
Milner applauded the move, noting, “The world is moving away from
animal experimentation. Sanger and the University of Cambridge are
absolutely right in exploring cellular alternatives to animal
testing because you can get misleading results.”