The checkered history of Pfizer’s Premarin family of drugs
Animals in Labs Article from

FROM The Fund for Horses
June 2021

The mares must wear rubber urine-collection bags at all times which causes chafing and lesions. For most of their 11-month pregnancies, these horses are confined to stalls so small that they cannot turn around or take more than one step in any direction.

Premarin Mares
Pregnant Mares on a “Pee Line” in Manitoba.

The name Premarin® spells out in its name what it is made from — PREgant MAres uRINe.

Pfizer’s Premarin® family of hormone replacement therapy drugs of today includes not only Premarin®, but also similarly manufactured pharmaceuticals — marketed at various times — under the names Prempro®, Premphase®, Provera® and later Aprela® (originally called Duavee or Duavive before its release). Add to the list Premplus which was developed by Wyeth until Pfizer came along and made them part of its empire.

Premarin®, Prempro® and Premphase® are typically prescribed to women to help reduce symptoms of menopause such as hot flashes and vaginal dryness.

Provera®, in combination with an estrogen-containing medicine, is used to relieve symptoms of menopause in women with an intact uterus. Provera® is also used to protect the lining of the uterus while the estrogens relieve the symptoms of menopause.




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